An idea I got in my head after looking at a Legacy deck with a similar concept. I wanted to see if I could modify it to be Standard viable.
The deck focuses on the concept of Tainted Remedy, using lifegain cards on your opponent directly in order to force them to lose life while you reap some of the benefits of controlling their board and drawing.
KEEP IN MIND: This deck is a concept, and will only be made if Oust is reprinted into Standard, as that is my replacement for Last Breath.
KEY CARDS:
Tainted Remedy: This is obviously the staple of the deck, and the main focus of a win condition. You want to get one of these out as soon as possible and focus on protecting it if you can.
Healing Hands: Used for saving your own skin in a pinch or getting the utility out of it while combo'd with Remedy. The draw power of it is also pretty nice.
Oust: Not quite as potent as a straight up Last Breath but the fact that it isn't limited to a Power, Toughness, or CMC cost makes this an easy pickup for the deck. While it does only delay them. You can also have the time to prep another one while you wait. Not to mention you can use it with Remedy.
Palace Siege: A decent card if you name Dragons when playing it. It allows yourself to sustain through the game pretty much guaranteed. Not to mention if you have Defiant Bloodlord, you can certainly make use of having them lose 4 life while you gain some for yourself each turn.
Utter End: Simply your basic removal. This can get rid of any non-land threat you don't want to deal with, and almost entirely removing it from their access by the sheer fact that the permanent is exiled as opposed to being put in their graveyard.
Dark Petition: A costly one, but it is a tutor, nonetheless. Not to mention when you cast it, if you're using the other instants and sorceries well, this means you can easily snag the Spell Mastery bonus of it and play Liliana, Heretical Healer
if you so desired, or even fetch for a Tainted Remedy if you either can't get one off or they get rid of your first one.