There are at least 3-4 different decks in here, and none of them are very well represented. The first step to improving it is to make the decision about what the deck actually is and how it wants to win. Is it mill, self-mill, Ooze combo, control, reanimator, or something else?

I'd like it to be self-mill w/Laboratory Maniac. Ooze works as a "fail-safe".

I'd also like Grimoire to be a part of the deck. Especially since, I'll be self-milling.

I'm not sure I get the "self"-mill here. The only card I see that mills yourself is Armored Skaab and Forbidden Alchemy. Undead Alchemist, Trepanation Blade, and Mindcrank all naturally mill your opponent. I suppose one Jace, Memory Adept that sticks is all you really need to mill someone?

I can target myself with Jace, so I can mill myself and not my opponent.

Have you thought about a 1 of Mirror-Mad Phantasm being in the graveyard and Necrotic Ooze paying the activated ability cost of Mirror-Mad Phantasm to self-mill? (of course Laboratory Maniac being on the field)

It works because it actually searches for that Mirror-Mad Phantasm card in the deck, and since its not there because you only have one in the deck and its in the graveyard, tadaa you win due to self-mill.

The other one is which I just noticed is not in your deck,

Is that since you have that infinite mana combo, where is the Increasing Confusion?

What I would do is -2 Heartless Summoning, -2 Black Sun's Zenith, -2 Doom Blade, -2 Grimgrin, Corpse-Born, -4 Think Twice, -2 Armored Skaab, -1 Leaden Myr and -1 Silver Myr

Add +1 Mirror-Mad Phantasm, +4 Drowned Catacomb, +2 Evolving Wilds, +1 Increasing Ambition, +4 Increasing Confusion, +4 Thought Scour

Is Laboratory Maniac ability considered an activated ability? I'm guessing no.

No he does not have an activated ability sadly, but he can use the activated abilities of all the myrs that I guess gets milled to activate infinite mana Increasing Confusion to self.

If he does keep it, it works really nicely with Mirror-Mad Phantasm being in the graveyard (and hopefully the Laboratory Maniac on the field).

But thats the way I would see it would even work.

How is the ability of Laboratory Maniac not an activated ability? It "activates" when you run out of cards in your library.

602.1. Activated abilities have a cost and an effect. They are written as "[Cost]: [Effect.] [Activation instructions (if any).]"

602.1a The activation cost is everything before the colon (:). An ability's activation cost must be paid by the player who is activating it.

Example: The activation cost of an ability that reads ", "tap symbol" : You gain 1 life" is two mana of any type plus tapping the permanent that has the ability.

Source: http://wiki.mtgsalvation.com/article/Activated_ability

Laboratory Maniac iirc is a Triggered Ability.

Hmm. I'm scrapping this deck, then.